MI to FL By: Marie69 Days: 2 Km: 0 Jackson, MI to Jacksonville, FL by these roads:  US-127,US-223,US-23,  -475, I-75, OHIO 15, US-23, OHIO 315, I-71 I-270 US-23, US-35, I-64, I-77, I-26, I-75.

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